Buy Temodar 250mg Capsules

Buy Temodar 250mg Capsules | Temozolomide 250mg

Generic Temozolomide 250mg - Temodar 250mg Capsules

Availability: In stock

$79.80

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Quantity Strength Unit Price Price Cart
5 Capsules Temodar 100 mg $79.80 $399.00
5 Capsules Temodar 250 mg $195.00 $975.00

Details

Temodar contains Temozolomide as the main pharmaceutical agent, which belongs to the group of Alkylating agents. Temodar is used for the treatment of Glioblastoma multiforme concomitantly in adult patients along with radiotherapy. It helps reduce the growth of cancer cells. Temodar interferes with the growth and multiplication of cancer cells, slowing their growth and spread in the human body.

 MECHANISM OF ACTION OF TEMODAR

 Mechanism of action of Temodar depends on the ability of alkylate/methylate DNA. This methylation damages the DNA and leads to the death of tumor cells. Some tumor cells are able to repair this type of DNA damage and therefore diminish the therapeutic efficacy of Temozolomide, by expressing a protein O6-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the0-6-methylguanine-DNA methyltransferase gene. Some tumors are more sensitive to killing by Temozolomide. The presence of AGT protein in brain tumors predicts poor response to Temozolomide and these patients receive little benefit from chemotherapy with Temozolomide.

 DRUG CONTRAINDICATIONS OF TEMODAR

  • The patients who are hypersensitive to Temodar and elements of the drug.
  • Patients who are suffering with bone marrow cancer should not take this medication.
  • If you are a pregnant woman, do not consume this medication as it may cause dangerous effect to the unborn baby.
  • Temodar should be used with cautious, if you are suffering kidney or liver disease.

 

DRUG INTERACTIONS OF TEMODAR

 Some drugs when used in combination Temodar, modify the action of the drug:

  • Valproic acid (Depakene and Stavzor)
  • Dexamethasone and Prednisone.
  • Avastin (bevacizumab)
  • Decadron ( Dexamethasone)
  • Lipitor (atorvastatin)
  • Norvasc ( amlodipine)
  • Tylenol ( acetaminophen)
  • Xanax ( alprazolam)
  • Zofran ( ondensetron)

 STORAGE of TEMODAR

 Temodar should be stored at room temperature 300 C. Keep this medicine in an air tight container and prevent  it from exposure to temperature, light and humidity. Place the drug in a dry and hygienic area.

 DOSAGE SCHEDULE

 This drug should be taken as directed by your health provider. Do not take an overdose. The initial dose prescribed of Temodar is 75 mg per day with radiotherapy and this is to be maintained for 6 cycles.

 IN CASE OF MISSED DOSE OF TEMODAR

 If you missed the dose of Temodar, take it as soon as you remember. But if it is already near the time for your next dose then skip the dose and resume your regular dose plan.

 IN CASE OF OVERDOSE OF TEMODAR

 Just in case of overdose immediately inform to your doctor and get some medical attention.

Temodar overdose symptoms include: hair loss, tachycardia and bradycardia (irregular heart beat).

 SIDE EFFECTS of TEMODAR

 Side effects observed while using Temodar

  • Skin rashes
  • Loss of memory
  • Insomnia (sleep problem)
  • Lowering the level of white blood cells
  • Loss of appetite
  • Severe headache and fever
  • Flu symptoms.
    • Seizures (convulsions)
    • Chills
    • Tachycardia and bradycardia
    • Abnormal bleeding from mouth
    • Rectum
    • Vagina
    • Liver problem
    • Hair loss
    • Jaundice (yellowing of skin and eyes)

  PRECAUTIONS AND WARNINGS

  • This medication should not be prescribed to pregnant women. It may cause harm to the fetus.
  • The patients who are suffering with renal impairment should be cautious while using this medicine.
  • The patients who are suffering with hepatic impairment should be very cautious while using this drug.
  • Patients who are receiving Temodar have been reported with fatal and severe hepatotoxicity.

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